Possible path:

sudo nano /etc/php.ini
sudo vim /etc/php5/apache2/php.ini

Commands to load new php.ini

//Restawrt web server
sudo service httpd restart.

//Restart web server
sudo service apache2 restart

//Reload all config (.ini) files
service apache2 reload

Reference:

• https://stackoverflow.com/questions/16213275/will-service-httpd-reload-reload-new-php-ini-settings